Nano-i is a handheld triboelectric electrospinning system that creates a customized nanofiber membrane directly on a wound at the point of care. Unlike pre-manufactured dressings, it generates a conformable protective layer in under 2 minutes, enabling treatment of irregular, curved, and large wound surfaces. The nanofiber membrane supports rapid hemostasis, infection prevention, moisture management, and tissue regeneration while maintaining strong tissue adhesion, biocompatibility, and biodegradability. Powered by a 3.7 V battery and using a cartridge-based design, Nano-i transforms electrospinning from a facility-based manufacturing process into a portable treatment platform for acute and chronic wound patients in clinical, home-care, emergency, military, and disaster-response settings.